JWH-018 Informations part 2 (update on side effects)

JWH-018 molecule structure

There are still not much real studies that had been done on the cannabinoid JWH-018, cause as written before, there is no interest coming from the pharmaceutical industry. But meanwhile it is still possible to make a list with certain of the side effects from the research chemical JWH-018.

Many of the negative experience reports are just made to spread fear of these cannabinoids or just people who want to make themselves important. This is why you can find so many reports on these research chemicals like "I smoked Spice once and had to go to the hospital cause of heart problems". Sometimes you even might read that someone died of a heart attack from these cannabinoids. But such an even would have attracted a great amount of media attention to JWH-018. Sometimes you also might find that someone in the age of 13 or 14 used Spice and had to go for a long trip into the hospital, but that doesn't seem to be a source of information to trust. Cause who is selling Spice or JWH-018 to a kid in the age of 13 or 14, if so, what else did they consumed etc. etc.

So it is hard to estimate which information sources on the topic of research chemicals, cannabinoids and especially JWH-018, you trust. One source I found quite helpful to put these JWH-018 informations here together was drugs forum. It has more than half a million readers per month and a reputation system, thus I was able to pick the posts of the most reliable writers and so be able to make a list of JWH-018 side effects that are true.

First it should be noted that underaged people shouldn't use cannabinoids, research chemicals or drugs at all. A child or growing up teen can't be rated like an adult, the body reacts totally different to drugs and poisons like research chemicals or JWH-018. So the JWH-018 informations given here are based on adults, not on teens and especially not on children. However, back to the main topic.

Important Note: Smoking blends or incense blends contain much less of the pure research chemicals, a tolerance development and dosing in the way it could be done with the pure cannabinoids are not possible!

JWH-018 side effects:

Psychological:

- The side effects coming from the cannabinoid JWH-018 are similar to the ones of natural THC, but through the way higher potency of the research chemical JWH-018 they are also far stronger, can occur  faster and more intense. With regular Cannabis it can happen that a person becomes psychotic, this is often represented by some sort of persecution mania. Of course this can also happen with the artificial cannabinoid JWH-018.

- If too much of the cannabinoid JWH-018 is taken, it can produce fear and panic attacks similar to THC. But through the higher potency of the cannabinoid JWH-018 it is more likely to happen and often even more intense. This is based on the binding affinity on the cannabinoid receptors in the body, THC is only a partial agonist, while the research chemical JWH-018 is a full agonist.

- Regular THC, as well as the research chemical JWH-018, can lead to a psychological dependency. But in most cases there is an already existing dependency on THC and the JWH-018 is used as legal high to replace the illegal usage of cannabis. If the research chemical JWH-018 is used as it is and not as replacement for an already existing cannabis dependency, it has interestingly a lower potential to cause dependency. But some consumers even report, that they could use the research chemical JWH-018 to get free of their cannabis addiction. This could have to do with the duration of effects and the longer after effects from cannabis. Through the long lasting after effects and through that the permanently existing feeling of being "down" it seems to be more likely to trigger the desire to use cannabis again, so more cannabis is used again. On the other hand the research chemical JWH-018 is leaving the consumer sober again a few hours after taking the cannabinoids.

Physiological:

- If the artificial cannabinoids JWH-018 are used permanently over months or even years, it can lead to significant problems on the digestive system. Consumers of JWH-018 often report that they always have a weird kind of diarrhea. For them it seems like the research chemical JWH-018 avoids the digestive system to absorb the water from the stool.

- Through permanently consuming JWH-018 it is also reported to have stomach upsets often after taking a meal without any reason.

- One paradox side effects from using the cannabinoids is also the disappearing of appetite enhancement, it even seems to than produce some sort of appetite suppression. The consumers have sometimes even reported to have no appetite anymore at all.

If the already mentioned side effects from using cannabinoids JWH-018 occur, the most users stop using the research chemical and the body recovers within the coming 2 weeks. But remaining long term effects can still not be estimated. Some users who are stronger affected by addiction to the cannabinoids ignore these warning signals from the body and continue using the cannabinoids. If this is happening the side effects on the body can become far more critical:

- The consumer of the cannabinoids JWH-018 is quickly loosing body mass and weight, cause he nearly stops eating completely.

- Weakness and sometimes even blackouts occur, it is yet not clear if this comes from the pure aspect of not eating enough or if the consumption of cannabinoids JWH-018 has also a direct effect on this.

- The remaining effects of JWH-018 make the consumer instantly very tired, it is barely possible to do something else besides sleeping after consuming the cannabinoids.

- If the consumer still not stops the usage of cannabinoids, especially JWH-018, there comes a weird and quite alerting effect into play. The consumed dosage of JWH-018 starts to decrease again with every further consumption, cause the user starts to feel uncomfortable with higher dosages or better said with his normal dosage. Of course this could be a pure psychological side effect, but in most cases such side effects are a sign of an organ failure (which one is not known). A similar symptom exists with alcoholism, first the liver actions are increasing, once the liver broke down, these actions are decreasing again, but for sure that is than no sign of getting better.

- If JWH-018 and other cannabinoids from the research chemical group are smoked and not vaporized, there are decomposition compounds that are sometimes visible with the bare eyes. If you watch closely, you can see small black spines flying in the air after burning a higher dosage of JWH-018 and for sure these are also inhaled while smoking it. Of course after doing this for a while, these black spines from the cannabinoids start to gather in the lungs, the user than starts to barf up large amounts of deep black slime. Even if the consumption of cannabinoids or JWH-018 is than stopped completely, it can take 3 to 6 months before the user stops barfing up black slime. It is unknown how dangerous this can be, but in general every foreign matter in the lungs is harmful. And if these are gathering up in large amounts, like after taking cannabinoids daily, some further side effects could include: Decrease of the lungs function, sepsis (toxins in the bloodstream) and also cancer development.

Further Notes and Safer use:

The side effects from cannabinoids and JWH-018, which are described here are based on strong and long lasting consumption, but for the reasons of safety, the research chemical JWH-018 should never be smoked directly. So this means that the JWH-018 or better said any cannabinoids or research chemicals should ever get in touch with a flame, they always should only be vaporized, this way of using these at least ensures that no foreign matter is reaching your lungs.
No matter if it is just about JWH-018, research chemicals in general or cannabinoids, they never should be used on a daily base and also not as permanent replacement for natural cannabis. Occasional usage of JWH-018 doesn't seem to be related on many side effects, cause most of its side effects are based on long term usage or extreme dosing.

Further it has to be divided if JWH-018 is used as pure research chemical or in the form of incense blends. Incense blends commonly only contain a small percentage of the cannabinoids and therefore are more similar to cannabis: If the user reaches a certain point of tolerance, it is barely impossible to enhance the dosage any further. But if the user is taking the pure research chemicals, cannabinoids or JWH-018, it is an easy thing to enhance the dosage. Like you can find in many JWH-018 experience reports and also in mine on this website, a large JWH-018 dosage is set between 1-2 mg, but there are many daily users who report about using 200-300 mg of the pure research chemical JWH-018 with every consumption! This means the enhancement of the JWH-018 dosage is done by a factor of 150x.

Conclusions: The usage of incense blends instead of the pure cannabinoid JWH-018 is a bit less dangerous, cause less of the pure research chemicals is used. Further the tolerance development is limited to a certain extend. If using the pure cannabinoids, vaporize them and not smoke them.
No matter what you consume, do it occasionally to avoid critical side effects.